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Friday, August 25, 2000

Pharmacology MCQ Explanation 114

Friday, August 25, 2000

D. Methemoglobinemia

Methemoglobinemia is a condition in which the iron within hemoglobin is oxidized from the ferrous (Fe2+) state to the ferric (Fe3+) state, resulting in the inability to transport oxygen and carbon dioxide.

Clinically, this condition causes cyanosis, often posing a diagnostic dilemma.

  • usually results from exposure to oxidizing substances (such as nitrates or nitrites, aniline dyes, or medications, including lidocaine, prilocaine, phenazopyridine hydrochloride (Pyridium], and others)


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